Viral blips and hidden infections: pitfalls in HIV-1 prophylaxis by broadly neutralizing antibodies

Back to the "HIV and Co-Infections News" list

A study, published in Nature, reveals that potent, broadly neutralizing antibodies (bNAbs) delay viremic simian immunodeficiency virus (SIV) infection in rhesus macaques but do not fully prevent subclinical infections. Despite bNAb concentrations being significantly higher than supposed protective thresholds, transient viral “blips” occurred, which suggests that bNAb prophylaxis can mask subclinical infections and has implications for the interpretation of HIV-1 prevention trials.

Read the full Research Highlight, published in Nature, here.

 

Source : Nature

Get involved

Are you living with HIV/AIDS? Are you part of a community affected by HIV/AIDS and co-infections? Do you work or volunteer in the field? Are you motivated by our cause and interested to support our work?

Subscribe

Stay in the loop and get all the important EATG updates in your inbox with the EATG newsletter. The HIV & co-infections bulletin is your source of handpicked news from the field arriving regularly to your inbox.