University of Toronto: Toronto team leads first-in-Canada case of sustained HIV remission

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University of Toronto news release

A team of clinicians and researchers at University Health Network (UHN), Unity Health Toronto and the University of Toronto have reported the first Canadian case of sustained HIV remission – and possible cure – in a 62-year-old man who received a bone marrow transplant to treat cancer.

The individual was first diagnosed in 1999 and has been living with HIV for 27 years, taking antiretroviral therapy (ART) throughout that time to suppress virus levels. He developed acute myelogenous leukemia in 2021 and underwent a bone marrow transplant at UHN’s Princess Margaret Cancer Centre with donor stem cells that were selected because they contain a rare “delta-32” mutation in the CCR5 gene.

The individual discontinued ART in July 2025 and, as of April 2026, is in sustained remission with HIV levels remaining undetectable. If he continues to have undetectable levels of HIV for two-and-a-half years after stopping ART, the Toronto patient would join a group of 10 individuals worldwide who are considered cured of HIV.

Read the full news release here.

 

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