Gladstone Institutes news release
Scientists have opened a new door to understanding HIV by creating the first comprehensive genetic roadmap of how the virus interacts with real human cells. The team identified a multitude of human proteins that either help the virus thrive or work to stop it.
Then they dove into understanding how the proteins function. Two of them stood out for their potent antiviral properties. Known as “PI16” and “PPID,” these proteins had never before been linked to HIV infection.
The team discovered that increased levels of PI16 can block HIV from fusing with T cells, which could stop infection before it even starts. PPID, on the other hand, acts on the virus after it enters the cell, limiting HIV’s ability to reach the nucleus and start making copies of itself.
Read the full news release here.
Source : Gladstone Institutes
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