CATIE: New analysis supports the use of Maviret for people with HCV infection and comorbidities

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CATIE news story

A team of researchers in several countries participated in a review of clinical trials of Maviret for the treatment of chronic HCV infection. The researchers were interested in the safety and tolerability of Maviret in people who had chronic health conditions in addition to chronic HCV. They were also interested in finding out how people who were taking multiple medications for these other chronic health conditions tolerated Maviret.

In an analysis of 6,547 participants in 21 clinical trials, the researchers found that despite many participants having co-existing conditions (comorbidities), overall Maviret was highly effective and well tolerated, with relatively few people discontinuing this treatment. What’s more, the researchers stated that “potential drug-drug interactions between [Maviret and a range of the following medicines should not be a barrier to initiating HCV treatment]:

  • antipsychotics
  • calcium channel blockers (a group of medicines used to treat high blood pressure and irregular heart rhythms)
  • beta blockers (a group of medicines used to treat abnormal heart rhythms and anxiety)
  • other medicines used to treat high blood pressure
  • drugs to lower cholesterol levels
  • opioids

Read the full news story here.

 

Source : CATIE

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