Women living with both HIV and hepatitis C virus (HCV) may be at especially high risk for severe liver disease, according to a large Canadian study. Researchers report that HIV and sex together influence the risk for HCV-related cirrhosis and liver decompensation, though not for liver cancer.
Researchers looked at the effects of HIV status and sex on cirrhosis, liver cancer and liver decompensation due to hepatitis C. The cohort included 65,151 people with hepatitis who were followed from 1999 to 2018. They measured the relative excess risk due to interaction of HIV status in women and men.
Women and men with hepatitis had different clinical outcomes according to HIV coinfection status. Women living with both HIV and HCV had a 44% greater risk of developing cirrhosis and were more than two and a half times as likely to experience liver decompensation as women with HCV alone.
Source : Cancer Health
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