Kaposi sarcoma responded to chemotherapy in a small prospective study of people living with HIV who maintained long-term viral suppression, although eight participants experienced relapse during follow-up. The findings suggested that treatment remained effective for some patients, but maintaining long-term disease control could prove challenging even when HIV was well controlled.
Kaposi sarcoma is a low-grade vascular tumour caused by Kaposi sarcoma herpesvirus (KSHV/HHV8). In people living with HIV, it is an AIDS-defining cancer that has become less common since the widespread use of combination antiretroviral therapy. However, prospective evidence describing treatment outcomes in patients with sustained HIV virological control has been scarce.
Source : European Medical Journal
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