University of Cape Town | Study links slower walking to cognitive decline in people living with HIV

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University of Cape Town news release

How fast people living with HIV walk could provide important clues about their brain health, a University of Cape Town study by the Department of Psychiatry and Mental Health’s Neuroscience Institute has found. The research links slower walking speeds to poorer cognitive performance and identifies changes in brain connectivity that may help explain the relationship.

The research, published in the Journal of NeuroVirology, found that among people living with HIV (PLWH), slower walking speed was significantly associated with poorer overall cognitive performance and functioning, particularly in memory and motor skills. This relationship was linked to changes in the brain’s frontoparietal network, a key network involved in executive functioning, attention and cognitive control.

The researchers found that PLWH who walked more slowly tended to have altered connectivity within this network, and these connectivity patterns were also associated with poorer executive function.

Read the full news release here.

 

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