Over half of the people carrying HIV experience chronic pain at some point, which is difficult to treat. Researchers used mice to explore how HIV leads to chronic pain.
Previous research separately linked a viral protein called glycoprotein 120 (gp120) to increased pain sensitivity and overactive signaling of a type of nerve receptor in the spine to nerve pain. Informed by these findings, the researchers sought to investigate whether gp120 influences signaling of this nerve receptor.
Source : Medical Xpress
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