University of Gothenburg: Early immune responses linked to protective HIV antibodies

Back to the "HIV and Co-Infections News" list

University of Gothenburg news release

Developing an effective HIV vaccine remains one of the major challenges in global health. One promising approach focuses on so-called broadly neutralizing antibodies, antibodies that can block many different variants of HIV. However, only a small fraction of people living with the virus develop these antibodies naturally.

In a study, researchers used a method that analyzes fragments of genetic material, known as cell-free RNA and DNA, circulating in the blood. This makes it possible to track immune responses, viral genetic variation, and other microbes from the same blood sample.

The researchers analyzed blood samples from 14 women in South Africa who were followed from before HIV infection through the first years after infection, before treatment began. In total, 42 samples collected at different time points were analyzed. By comparing individuals who later developed broadly neutralizing antibodies with those who did not, the researchers examined how early immune responses differed during infection.

Read the full news release here.

 

Get involved

Are you living with HIV/AIDS? Are you part of a community affected by HIV/AIDS and co-infections? Do you work or volunteer in the field? Are you motivated by our cause and interested to support our work?

Subscribe

Stay in the loop and get all the important EATG updates in your inbox with the EATG newsletter. The HIV & co-infections bulletin is your source of handpicked news from the field arriving regularly to your inbox.