CATIE news story
As people with HIV live longer, they become at risk for aging-related issues—typically, type 2 diabetes, high blood pressure, arteriosclerosis, and so on. Another consequence of aging is that cells can accumulate changes (mutations) to their genes. Some of these changes are unfavourable; they increase the risk for cells to follow a development pathway that leads to abnormal cellular growth and heightens the potential for the formation of pre-cancers and cancers.
The immune system plays an important role in detecting and eliminating abnormal and pre-cancerous cells (as well as cancers). However, as everyone ages (regardless of HIV status), their immune systems become slightly weaker and less effective at eliminating pre-cancers and cancers.
Thus, it is important to conduct long-term studies of ART users to monitor their risks for different cancers. Findings from such studies can help inform care guidelines for people with HIV.
A team of researchers from 184 clinics in France collected health-related information from people using ART. In the past, the French Hospital Database has produced useful reports, as it has detailed records.
The latest analysis from the database focused on cancer risk in ART users. The researchers compared their findings to those from about 20% of the French population that did not have HIV, some of whom also developed cancer within the study period.
Read the full news story here.
Source : CATIE
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