Using doxycycline for prophylaxis of bacterial STIs: considerations for the European Union and European Economic Area

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On 28-29 June 2023, the European Network for Sexually Transmitted Infections (STI) composed of epidemiological and microbiological experts nominated by European Union/European Economic Area (EU/EEA) countries met in Stockholm, Sweden. One of the sessions in this meeting was dedicated to the use of doxycycline for the prevention of bacterial STIs and was co-chaired by a principal expert antimicrobial resistance and healthcare associated infections at ECDC and the chair of the International Union against Sexually Transmitted Infections (IUSTI) Europe. The objectives of the session were: (i) to provide an update on the evidence of efficacy of doxycycline taken before, during, or after unprotected sexual contact in reducing the incidence of chlamydia, gonorrhoea and syphilis; (ii) to present considerations on the impact of the widespread use of doxycycline on antimicrobial resistance of bacterial STIs, other pathogens and commensals, and; (iii) to discuss the potential benefits and harms of doxycycline prophylaxis at individual and public health levels, with a focus on EU/EEA context. Presentations by two invited keynote speakers were followed by an interactive discussion session among the STI Network members led by the co-chairs.

Access the report from the meeting here.

 

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