A new long-acting HIV treatment could expand options for people who have trouble taking daily pills and whose virus is resistant to some commonly used HIV drugs.
The only approved long-acting combination pairs cabotegravir with rilpivirine. But HIV can develop resistance to rilpivirine and related drugs, limiting its use for some people. Moreover, rilpivirine is not available in low- and middle-income countries.
The new approach replaces rilpivirine with lenacapavir, a long-acting drug that attacks HIV in a different way. In the new study, all the participants achieved and maintained control of the virus.
Source : UCSF
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