TheBodyPro | Liver disease in women with HIV: A new study may change our clinical considerations

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TheBodyPro | Expert analysis from Benjamin Young, M.D., Ph.D.

For those of us who are accustomed to seeing liver disease through a virology lens, new data from an all-women U.S. cohort provide a critical new perspective: Modern-day steatotic liver disease (SLD) is extremely common — even outside of viral hepatitis coinfection — and its relationship to HIV is more complicated than we may have previously realized.

Key Takeaways

  • Steatotic liver disease prevalence was 47%, regardless of HIV status, in a cohort of U.S. women; body mass index and diabetes were major predictors.
  • Among women with steatotic liver disease, HIV was associated with 48% greater adjusted odds of clinically significant fibrosis.
  • It is important for HIV clinicians to assess fibrosis risk alongside metabolic factors, and resist assumptions to blame antiretroviral therapy or conclude that steatosis alone indicates significant liver disease.

Read the full analysis here.

 

Source : TheBodyPro

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