The latest major study exploring the role of antiretrovirals in weight gain has arrived — and its findings don’t fit neatly into either side of the debate. A new, massive analysis out of the U.S. appears to affirm that, on balance, some integrase inhibitors do have a larger impact on body weight than other drugs. But the devil is very much in the details — and those details include an important signal regarding Black women in particular, as well as some important takeaways for how we can best broach this subject with all of our patients living with HIV.
This was a retrospective observational cohort study using data from the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD), which includes 27 HIV cohorts across the United States and Canada. The analysis included 32,514 people across 13 cohorts with sufficient longitudinal weight data; all individuals initiated antiretroviral therapy between January 2007 and December 2021.
Source : TheBodyPro
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