Are we ever going to see broadly neutralizing antibodies (bNAbs) emerge as a widely utilized HIV treatment method? It still feels too early to place any bets, but newly published results from the much-heralded RIO study are certainly cause for optimism. They allow us to envision a future in which a combination of approaches helps our patients live untethered from the need to take HIV medications daily (or weekly, or monthly, or quarterly).
This analysis reports the 20-week results of RIO, a double-blind, randomized, placebo-controlled study evaluating whether two long-acting bNAbs could delay HIV rebound after participants stopped antiretroviral therapy. The two bNAbs, called 3BNC117-LS and 10-1074-LS, target conserved regions on the HIV envelope glycoprotein and can neutralize a broad range of HIV strains.
Source : TheBodyPro
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