Elizabeth Glaser Pediatric AIDS Foundation/DFID – UK Department for International Development/FlickrA study published in AIDS compared children with and without HIV and found consistently lower bone growth and bone turnover in children living with HIV. The children were all from similar backgrounds and the children living with HIV in the study had well controlled HIV, in most cases. Dr Yanhan Shen and her colleagues found that children on ritonavir-boosted lopinavir had lower bone mass and higher inflammatory markers than those taking efavirenz.
There are many factors that can adversely affect bone growth and child skeletal health, including malnutrition and infectious diseases. Effective bone development is important, not just for growth in childhood but in preventing osteoporosis and bone fractures later in life. Chronic inflammation seems to contribute to bone loss and disrupts mechanisms which regulate the formation and breakdown of bones.
Read the full story at Aidsmap.
Source : Aidsmap
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