Resistance history does not affect response to dolutegravir/lamivudine

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A history of virologic failure on antiretroviral treatment does not affect the response when people who are virally suppressed switch to a two-drug regimen of dolutegravir and lamivudine (Dovato), even if they have resistance to lamivudine, results of the SOLAR-3D study show.

Presenting SOLAR-3D last month at the 12th International AIDS Society Conference on HIV Science (IAS 2023) in Brisbane, Dr Gary Blick said the findings had the potential to reduce drug costs and drug exposure for people who are not currently eligible for treatment with a two-drug regimen of dolutegravir and lamivudine.

A two-drug regimen of dolutegravir and lamivudine (Dovato) is currently recommended as a switch option for treatment-experienced people with HIV who are virologically suppressed, but only if they have no history of treatment failure and no prior or current resistance to either dolutegravir or lamivudine.

Read the full story at Aidsmap.

 

Source : Aidsmap

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