Ragon Institute news story
A new study demonstrated that HIV escapes broadly neutralizing antibodies (bNAbs) through a limited set of conserved mutation paths, and that manipulating the cost of those paths can dramatically improve therapeutic outcomes.
Broadly neutralizing antibodies are among the most promising tools for treating and preventing HIV. Unlike conventional antiretroviral drugs, bNAbs target the virus’s surface directly and can block infection across many strains. But clinical trials have repeatedly shown that HIV can evolve resistance, undermining the antibodies’ effectiveness. Understanding how and why the virus escapes has remained a central challenge.
Read the full news story here.
Source : Ragon Institute
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