Hiroshima University press release
Researchers examined the use of novel biomarkers to accurately determine hepatocellular cancer (HCC) risk in chronic hepatitis B patients. Specifically, they showed that hepatitis B viral RNA (HBV RNA) is better for this purpose compared to both currently used biomarkers as well as other proposed biomarkers.
“Our study demonstrates for the first time that among patients with undetectable HBV DNA, those who test positive for serum HBV RNA have a significantly higher risk of developing HCC. We found that HBV RNA shows better predictive performance than HBcrAg,” researchers said. “Since HBV is a DNA virus, HBV RNA has not received much attention. Although HBV RNA is produced during the viral replication cycle, we found it quite surprising that it could serve as such a powerful predictor of cancer development.”
Read the full press release here.
Source : Hiroshima University
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