Precision BioSciences announces Phase 1 safety and efficacy for cohort 1, lowest dose level in ELIMINATE-B, a first-in-human trial of PBGENE-HBV for chronic hepatitis B
Proof-of-activity now established for PBGENE-HBV, the first and only clinical modality designed to eliminate covalently closed circular DNA (cccDNA) and inactivate integrated DNA, with the goal of complete cure.
Vir Biotechnology successfully initiates all trials in ECLIPSE registrational program for chronic hepatitis delta
Vir Biotechnology announced the enrollment of the first participant in ECLIPSE 3. All three trials in the Company’s registrational ECLIPSE program for chronic hepatitis delta (CHD) have now been initiated. ECLIPSE 3 is a Phase 2b trial designed to compare the combination of tobevibart and elebsiran to bulevirtide treatment in patients with CHD. ECLIPSE 3 will provide important supportive data to help establish access and reimbursement in key markets.
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