ShutterstockA study published in AIDS found that people who already had some evidence of decreased kidney function on blood tests or who were aged over 50 were significantly more likely to develop kidney impairment when taking tenofovir disoproxil as pre-exposure prophylaxis (PrEP). The risk of kidney damage when taking PrEP was found to be low, although it may have been underestimated in previous clinical studies.
The findings suggest that people in these two higher risk groups may require more monitoring when using PrEP. Similarly, event-based PrEP or tenofovir alafenamide-based regimens provide potentially less harmful alternatives for those with kidney damage, but more evidence is needed.
Read the full story at Aidsmap.
Source : Aidsmap
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