Drug levels may influence efficacy as much as resistance
AidsmapUsing the antibiotic doxycycline to prevent the bacterial STIs gonorrhoea, chlamydia and syphilis (‘doxyPEP’) has sparked fears that it may lead to widespread drug resistance, especially in the gonorrhoea bacterium.
However, an analysis of gonorrhoea resistance seen among participants in the US DoxyPEP study shows that while resistance to doxycycline and other drugs of its class is not uncommon, only modest increases in the proportion of gonorrhoea infections with significant resistance were seen, and that there was little difference in resistance rates between people taking doxyPEP and not taking it.
Read the full story at Aidsmap.
Source : Aidsmap
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