Medical Xpress news story
In the ongoing effort to find new therapeutics for infants born infected with HIV, an international team of investigators has discovered that babies can tolerate treatment with anti-HIV antibodies.
While the first studies in adults involving anti-HIV antibodies were conducted in the late 1990s, it has taken until now for medical investigators to test the feasibility of an antibody strategy for babies as young as 12 weeks.
Conducting their research on three continents — North America, Africa and Asia — researchers hoped to cripple one of the worst aspects of HIV: its ability to become a dormant stowaway in key immune cells.
The researchers conducted a clinical trial that combined antiretroviral drug therapy with broadly neutralizing antibodies, proteins designed to block HIV’s key glycoprotein — gp120. The virus uses that glycoprotein to break into human cells.
Read the full news story here.
Source : Medical Xpress
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