King’s College London news story
Researchers have created a unique collection of human stem cell models which could help to uncover why HIV leads to different outcomes in different people.
They generated a cell bank of a special type of stem cell (called induced pluripotent stem cells or iPSCs) from 18 people living with HIV, creating a long-lasting research resource that can be used to model HIV infection in the laboratory. The 50 iPSC lines were derived from participants in the Multicenter AIDS Cohort Study (MACS), representing a wide range of disease trajectories.
People living with HIV experience the disease in markedly different ways. While some individuals develop severe illness quickly, others remain healthy for many years. These differences cannot be fully explained by the virus or environment alone, as host genetics play a significant role in shaping disease progression.
Read the full news story here.
Source : King’s College London
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