Johns Hopkins University news release
Antiretroviral drugs for HIV infection have enabled most people living with the virus to live long and healthy lives. However, a small portion of people experience detectable — and worrisome — traces of the virus that causes AIDS despite strict adherence to long-term treatment regimens and the absence of symptoms.
New findings published in Nature Communications suggest that most cases of this phenomenon, which is called non-suppressible viremia, are explained by defective and noninfectious copies of the virus.
The study, which involved more than 50 people, found that while traces of HIV-1 RNA can persist in blood after optimal therapy, cases of non-suppressible viremia are driven by HIV-1 RNA with defects in a piece of the RNA known as 5′-leader.
Read the full news release here.
Source : Johns Hopkins University
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