For the first time, and thanks to spatial imaging techniques, a clinical trial shows how antiretroviral drugs are distributed within human lymph nodes and claims that they reach areas where HIV-infected cells persist.
The results of the clinical trial, published in Nature Communications, show that the combination of dolutegravir and lamivudine not only reaches the lymph nodes and is efficiently distributed in areas where virus-infected cells predominate, but also manages to rapidly reduce the HIV reservoir during the first year of treatment.
Source : IrsiCaixa
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