Infectious Disease Special Edition: Investigational drug TBD09 holds promise for TB

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Infectious Disease Special Edition news story

The investigational antibiotic TBD09 could have the potential to treat TB with less toxicity, according to new research.

The preclinical study, published in Nature Medicine, shows that TBD09, also called MK-7762, had strong efficacy in animal models with a favorable safety profile. These results, and favorable phase 1 data, indicate TBD09 may hold promise for TB.

TBD09 is an oxazolidinone, the same class as linezolid.

Read the full news story here.


For more TB updates, check out the TB CAB Weekly Newsletter (Issue #4, 1 February 2026).

The newsletter is brought to you by the Global TB Community Advisory Board (TB CAB) with the support of Treatment Action Group (TAG) and the European AIDS Treatment Group (EATG). Subscribe to the newsletter here.


 

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