Infectious Disease Advisor news story
Switching to a 2-drug antiretroviral therapy (ART) regimen containing an integrase strand transfer inhibitor plus a nucleoside reverse transcriptase inhibitor (INSTI+NRTI) is highly effective and well tolerated among virologically suppressed patients with HIV, according to study findings published in HIV Medicine.
Investigators conducted an observational cohort analysis (COMBINE-2) to evaluate real-world effectiveness and safety outcomes among adults with HIV who switched to an oral INSTI+NRTI dual ART regimen while already suppressed (viral load <50 copies/mL). They enrolled patients from 28 clinical sites across Europe, including hospitals in the United Kingdom, Spain, France, Belgium, Italy, and Portugal.
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Source : Infectious Disease Advisor
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