Adults with HIV aged 60 years and older are more likely to report favorable quality of life (QOL) following a switch in antiretroviral therapy (ART) than adults younger than 60 years, according to study findings published in HIV Medicine.
Older adults represent a growing proportion of people with HIV, but evidence regarding patient-reported outcomes among those aged 60 years and older remains limited.
Researchers assessed whether advanced age was associated with reasons for ART modification, QOL, and clinical outcomes among adults with HIV who switched to bictegravir-based 3-drug regimens (BIC 3DR) or dolutegravir-based 2-drug regimens (DTG 2DR). They performed a cross-sectional evaluation of prospectively gathered data from an ongoing cohort involving 11 hospitals in Spain that began enrollment in 2018. The analysis included adults with HIV aged 50 years and older who switched to BIC 3DR or DTG 2DR in routine clinical practice. Participants were grouped according to whether they were younger than 60 years or aged 60 years and older at the time of treatment modification.
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Source : Infectious Disease Advisor
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