Infectious Disease Advisor news story
Patients with HIV who achieve immune reconstitution on long-term antiretroviral therapy (ART) have rates of community-acquired pneumonia (CAP) and herpes zoster (HZ) comparable to those seen in the general population, whereas substantially higher risks persist among individuals with low CD4+ counts or limited ART exposure, according to study findings published in Clinical Infectious Diseases.
Although vaccination against pneumococcal disease and HZ is recommended for all patients with HIV, uncertainty remains regarding optimal timing, particularly in relation to age, CD4+ count, and duration of ART. To address this gap, investigators conducted a longitudinal cohort study to evaluate how these factors jointly influence the incidence of CAP and HZ in the modern ART era.
The investigators sourced data from the ATHENA National Observational Cohort, which captures more than 97% of patients with HIV receiving care in the Netherlands.
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Source : Infectious Disease Advisor
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