More attention should be paid to modifiable risk factors for chronic liver disease in people with HIV, such as alcohol, metabolic disorders and being overweight, HIV and hepatology specialists in Brighton, England report in the Journal of Acquired Immune Deficiency Syndromes.
In a study of people with HIV who had abnormally high liver enzyme levels, they found that one in five had clinically significant liver damage and 60% had risk factors that could be modified by treatment of metabolic complications and/or abstinence from alcohol.
They also found that past treatment with a first-generation antiretroviral drug, didanosine (ddI), increased the risk of both clinically significant fibrosis and moderate-to-severe fat accumulation in the liver.
Source : Aidsmap
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