The latest update to the European HIV guidelines from EACS, released at the HIV Congress in Glasgow, includes a new recommendation that everyone should start PrEP with a double dose.
This is irrespective of sex, gender or whether subsequent dosing will use daily or on-demand.
The recommendation is based on providing rapid protection (within two hours), based on pharmacokinetic and pharmacodynamic studies. In last year’s guidelines, starting with a double dose was only recommended for cisgender men using on-demand 2:1:1 dosing. Otherwise, daily dosing for seven days was recommended for everyone else before relying on protection and from daily PrEP.
Read the full report by Simon Collins, HIV i-Base here.
All HIV i-Base reports from HIV Glasgow 2024 can be accessed here.
Source : HIV i-Base
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