The emergence of high-level dolutegravir resistance was extremely rare in people switched to first-line dolutegravir-based treatment in Zambia and Malawi, a large prospective study has found.
But the risk of having unsuppressed HIV one and two years after switching was six to seven times higher in people who switched to dolutegravir with detectable HIV. The researchers say their findings emphasise the importance of viral load monitoring before switching.
Source : Aidsmap
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