Dolutegravir has direct effects on fat cells

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The integrase inhibitor dolutegravir suppresses the production of a key signalling chemical in fat cells that is also suppressed in obesity, Spanish researchers report in the journal Life Sciences.

The finding that dolutegravir suppresses the production of adiponectin, a chemical secreted by fat tissue that regulates insulin sensitivity, confirms research carried out by a French research group, and provides further evidence that dolutegravir can have direct effects on the human cells that store fat.

Read the full story at Aidsmap.

 

Source : Aidsmap

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