[CROI 2026] Medscape: Cerebrospinal fluid biomarkers suggest impact of herpes on brain health in people with HIV

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Medscape news story

Underlying herpes infection may have an impact on brain health in people with HIV (PWH), according to new data presented at CROI 2026.

Although most PWH are also infected with herpes viruses, the impact of the resulting immune response on brain health disorders has not been well studied.

Cerebrospinal fluid (CSF) biomarkers have been linked to latent herpes infection, particularly Epstein-Barr virus (EBV). The researchers conducted tests on PWH to look for signs of inflammation in both the blood and the brain. They measured peripheral blood mononuclear cells to check for cytomegalovirus (CMV) and EBV, as well as HIV DNA; they also measured CMV and EBV in plasma and 11 biomarkers in CSF.

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Source : Medscape

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