[CROI 2026] HIV i-Base: 11 mg dose selected for once-monthly MK-8527 for phase 3 PrEP studies

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HIV i-Base news story

A second study presented at CROI 2026 reported on the studies that led to selecting the 11 mg dose of MK-8527 (the successor compound to islatravir) that will be used in a once-monthly oral formulation in phase 3 PrEP studies.

This was decided based on PK results using doses from 6 mg to 12 mg from five phase 1 studies and one phase 2 study.

Read the full news story here.


View all HIV i-Base reports from CROI 2026


 

Source : HIV i-Base

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