Success in HIV management often comes down to the details, and as clinicians increasingly embrace long-acting injectables, one detail is proving critical: hepatitis B virus (HBV) status. At CROI 2026, the conversation shifted to a growing safety concern — the potential for HBV reactivation in patients transitioning away from tenofovir-based oral antiretroviral therapy (ART). Laurence Brunet, PhD, of Epividian, and Gerald Pierone, MD, chief medical officer of Whole Family Health Center, sat down to parse new findings that reveal how often baseline HBV screening is missed in clinical practice, creating a preventable risk for patients making the switch.
Source : AJMC
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