Three experimental injectable antiretrovirals – a novel capsid inhibitor and two next-generation integrase inhibitors – could be components of future long-acting HIV treatment regimens, according to study results presented at CROI 2026.
Pharmacokinetic data showed that ViiV Healthcare’s investigational capsid inhibitor VH-499, ViiV’s next generation integrase inhibitor VH-184 and Gilead Sciences’ pipeline integrase inhibitor GS-3242 could potentially be administered by injection just twice a year. All three drugs were safe and generally well tolerated, and phase II studies are expected to start this year.
Source : aidsmap
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