Two studies of children with HIV presented at the 13th International AIDS Society Conference on HIV Science (IAS 2025) in Kigali, Rwanda showed that even if they are on antiretroviral therapy (ART) and have fully suppressed viral loads, they carry markers of chronic immune activation that could lead to premature cardiovascular disease and other non-AIDS-defining conditions.
One of the studies linked this to the amount of intact proviral DNA they carry in their ‘reservoir’ cells; as other studies have previously shown, this was significantly lower in children who received ART shortly after birth.
Source : aidsmap
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