Compared with daily oral tenofovir disoproxil fumarate/emtricitabine (TDF/FTC), long-acting cabotegravir (CAB-LA) maintained robust efficacy, regardless of sexually transmitted infection (STI) incidence, according to study findings published in Clinical Infectious Diseases.
Researchers conducted an analysis of a double-blind, double-dummy randomized controlled trial (HPTN 083) to examine whether CAB-LA maintained protective efficacy when bacterial STIs were present. Transgender women and cisgender men who have sex with men were assigned 1:1 to receive active CAB-LA with TDF/FTC placebo or active TDF/FTC with CAB-LA placebo.
Source : Infectious Disease Advisor
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