Bioengineering: HIV-related liver disease: A new era emerges

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Bioengineering review

As individuals infected with HIV experience increased longevity, the landscape of health challenges associated with HIV has shifted dramatically. Notably, non-AIDS-related mortality has surged, with liver disease emerging as a leading cause of death in this population. The epidemiology of liver diseases is complex, encompassing a diverse range of conditions, including viral hepatitis, metabolic dysfunction-associated steatotic liver disease (MASLD), and liver cancer. This evolutionary shift necessitates a detailed examination of the multifactorial landscape of liver disease among people living with HIV.

Recent findings highlight a concerning rise in various liver diseases, driven by factors that go beyond traditional viral infections. The complexities of HIV infection can exacerbate liver conditions, making it critical to address the interplay of these diseases. Many individuals with HIV co-infected with hepatitis B or C virus are at a heightened risk for liver-related complications. The study, published in Nature Reviews Gastroenterology & Hepatology, underscores the urgent need for systematic screening and management strategies to mitigate liver disease burden in this population.

Read the full review here.

 

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