An experimental combination pill containing islatravir and ulonivirine shows promise as a weekly oral treatment option, according to study results presented at AIDS 2026.
Merck’s islatravir is the first nucleoside reverse transcriptase translocation inhibitor, which interferes with the HIV enzyme in a different way than familiar nucleoside/nucleotide reverse transcriptase inhibitors. A once-daily pill combining islatravir and doravirine, sold as Idvynso, was approved in the US in April.
Ulonivirine (formerly known as MK-8507) is a next-generation non-nucleoside reverse transcriptase inhibitor with activity against HIV strains that have developed resistance to older drugs in its class.
Source : aidsmap
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