People with HIV who developed COVID-19 during the second wave of South Africa’s pandemic in 2021 were more likely to experience a severe illness than HIV-negative people and more likely than people with HIV in the first wave to show low CD4 counts and other immune disturbances, South African researchers report in the journal eLife.
The researchers say their results suggest that the Beta variant of SARS-CoV-2 that predominated in South Africa’s second wave of COVID-19 leads to more severe disease in people with HIV because this variant interacts with HIV to deplete CD4 cells essential for viral control and promote a more severe inflammatory response.
Read the full story at Aidsmap.
Source : Aidsmap
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