NIH-funded clinical trial shows mobile units may help overcome significant barriers to accessing HIV and addiction treatment, but replication is needed.
Results from a clinical trial funded by the National Institutes of Health (NIH) in five major United States cities show that delivering integrated HIV and substance use disorder services using peer navigation in mobile medical units reduced all-cause deaths by 71% compared to participants who received peer navigation to community-based services alone. While scientists found no difference in the use of daily, oral PrEP and medication for opioid use disorder (MOUD) between the groups, the secondary outcome of reduced mortality was significant.
The trial, known as the HIV Prevention Trials Network Study 094 (HPTN 094), enrolled 409 adults without HIV, who injected drugs, had opioid use disorder, who were not taking MOUD at enrollment, and who were willing to consider MOUD. The trial took place in Houston, Los Angeles, New York City, Philadelphia, and Washington, D.C. One group received 26 weeks of peer navigation plus integrated PrEP, MOUD, and limited clinical and supportive services delivered on a mobile unit. The other group received 26 weeks of peer navigation services that linked participants to available non-mobile community services.
Source : National Institutes of Health
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