German Center for Infection Research (DZIF) news release
HIV may be suppressed by antiretroviral therapy, but its genetic material remains in the body. New research suggests that some of these viral remnants may be doing more than simply lingering: integration of HIV in specific genes, such as the BACH2 master regulator, can change the biology of the cell carrying it. This pushes CD4 T cells towards a state that favours long-term survival, continued division and altered immune activity. This observation may explain why HIV is able to persist for so long in the body of infected people. The results were published in the journal PLOS Pathogens.
Read the full news release here.
Source : DZIF
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