aidsmap news story
A new class of drugs called CD4 mimetics could be used to sensitise the immune system to HIV.
It is becoming clear that broadly neutralising antibodies, whether infused as a drug or generated by a vaccine, may not be sufficient to cure HIV, or even to lead to long-term remission off antiretroviral therapy.
Studies of the immune response to HIV in people who have managed to stay off antiretroviral therapy for prolonged periods without developing significant viral loads have found that their CD8 cells, which are the prime movers in the destruction of virally-infected cells, had preserved their ability to proliferate and respond afresh to new waves of HIV replication. The researchers called this capacity “stemness” because the cells preserved some characteristics of newly-produced stem cells – they were able to combat new waves in infection instead of becoming exhausted.
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View all aidsmap reports from AIDS 2026
Source : aidsmap
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