[AIDS 2026] aidsmap: Long-acting injectable treatment superior to daily pills for adolescents in African trial

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aidsmap news story

Eight-weekly injectable treatment with cabotegravir and rilpivirine proved superior to oral daily treatment with dolutegravir and two other drugs in maintaining viral suppression among adolescents in Africa, researchers from the LATA study reported at AIDS 2026.

Adolescents often experience difficulties in adhering to daily oral antiretroviral treatment and have poorer treatment outcomes than adults. Several studies have shown that adolescents who switch from oral to injectable antiretroviral treatment prefer injections and do not experience virologic rebound.

The LATA trial is the first randomised comparison of injectable treatment and oral antiretroviral treatment in adolescents. The study compared standard oral antiretroviral treatment with dolutegravir, tenofovir disoproxil and lamivudine to injections of cabotegravir and rilpivirine every eight weeks.

Read the full news story here.


View all aidsmap reports from AIDS 2026


 

Source : aidsmap

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