Long-acting injectable cabotegravir plus rilpivirine (CAB+RPV) maintains virologic suppression among individuals with HIV and obesity, with effectiveness and tolerability comparable to individuals without obesity. These findings suggest obesity may not meaningfully compromise outcomes with this injectable antiretroviral therapy regimen, according to study results published in HIV Medicine.
Investigators conducted an ambispective, multicenter real-world cohort study including adults with virologically suppressed HIV-1 infection who transitioned to injectable CAB+RPV between June 2023 and December 2024. Of 3203 individuals initially recruited, 3146 had suppressed viral loads at baseline and were included in the analysis. BMI data were reported for 2736 participants, including 362 (11.5%) classified as having obesity (BMI ≥30 kg/m²).
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Source : Infectious Disease Advisor
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