Two doses of the widely used HPV vaccine Gardasil9 produced an immune response identical to the standard three-dose regimen in women with well-controlled HIV, according to a study by Dr Deborah Konopnicki and colleagues published in the journal Clinical Infectious Diseases.
The World Health Organization (WHO) currently recommends a three-dose schedule for people living with HIV as opposed to two doses in the general population, due to concerns about potentially reduced immune responses. However, the study explored whether two doses might be sufficient for women with HIV who have stable immune function. Their results showed that antibody levels − commonly used as a proxy for vaccine efficacy − were effectively the same in the two- and three-dose groups against all nine types of the virus the vaccine protects against.
Source : aidsmap
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