The overall benefits of COVID-19 vaccines far outweigh potential risks, according to a recent study of 99 million vaccinated people – despite a number of misleading and sensational reports about the study. The study, published in the journal Vaccine in mid-February, aimed to get more precise estimates of the risk of adverse events following vaccination.
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According to results of a study published in the Journal of the Pediatric Infectious Diseases Society, the benefits of receiving primary series mRNA COVID-19 vaccines outweigh the risks for children and infants aged 6 months to 4 years, regardless of underlying medical conditions or infection-induced immunity.
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A much higher percentage of the population has experienced “persistent” COVID-19 infections lasting more than 30 days than initially assumed, according to new research by the University of Oxford. The study, published in Nature, found that one to three of every 100 infections may last a month or longer.
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The novel COVID-19 treatment, ensitrelvir, shows both clinical symptom improvement and an antiviral effect in a predominantly vaccinated population regardless of risk factors. Ensitrelvir is a 3CL protease inhibitor; 3CL protease is an enzyme that is essential for the replication of SARS-CoV-2. The FDA granted ensitrelvir a Fast Track designation; it is approved in Japan and Singapore and distributed under the name Xocova.
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The clinical trial is a 32-week randomized, 252 patient, double-blind, placebo-controlled, multicenter study that is evaluating the safety and efficacy of maraviroc and atorvastatin for the treatment of patients living with Long COVID/Post-Acute Sequelae of COVID (PASC).
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Susceptibility to SARS-CoV-2, the virus that causes COVID-19, did not differ by HIV serostatus in a Swiss study of individuals who were mostly virally suppressed, but it was lower among smokers compared to non-smokers. Most participants living with HIV were virally suppressed.
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